Jacob Plieth on X: "Max Mamonkin (Baylor) suggesting CAR clustering as a reason for tonic signalling (i.e., signal in absence of antigen) #CARTCR https://t.co/Lmwld40Iue" / X
Context matters in CAR T cell tonic signaling | Nature Medicine
Transient rest restores functionality in exhausted CAR-T cells through epigenetic remodeling | Science
Multi-antigen-targeted chimeric antigen receptor T cells for cancer therapy | Journal of Hematology & Oncology | Full Text
Endogenous TCR tonic signaling facilitates T-cell differentiation and... | Download Scientific Diagram
Counteracting CAR T cell dysfunction | Oncogene
Engineering γδT cells limits tonic signaling associated with chimeric antigen receptors | Science Signaling
Frontiers | Revolution of CAR Engineering For Next-Generation Immunotherapy In Solid Tumors
CAR-T design: Elements and their synergistic function - eBioMedicine
Rational Tuning of CAR Tonic Signaling Yields Superior T-Cell Therapy for Cancer | bioRxiv
Rational Tuning of CAR Tonic Signaling Yields Superior T-Cell Therapy for Cancer | bioRxiv
CAR-T design: Elements and their synergistic function - eBioMedicine
Tonic-signaling chimeric antigen receptors drive human regulatory T cell exhaustion | PNAS
New mechanism in preventing CAR-T cell exhaustion
Tonic Signals: Why Do Lymphocytes Bother?
Tonic GD2.28z CAR signaling is antigen independent. (a) In vitro 51Cr... | Download Scientific Diagram
Exhaustion of CAR T cells: potential causes and solutions | Journal of Translational Medicine | Full Text
Tonic 4-1BB Costimulation in Chimeric Antigen Receptors Impedes T Cell Survival and Is Vector-Dependent - ScienceDirect
Frontiers | Expanding the Therapeutic Window for CAR T Cell Therapy in Solid Tumors: The Knowns and Unknowns of CAR T Cell Biology
Cells | Free Full-Text | Limitations in the Design of Chimeric Antigen Receptors for Cancer Therapy
Tuning charge density of chimeric antigen receptor optimizes tonic signaling and CAR-T cell fitness | Cell Research
Tonic Signaling and Its Effects on Lymphopoiesis of CAR-Armed Hematopoietic Stem and Progenitor Cells
Physiological lentiviral vectors for the generation of improved CAR-T cells: Molecular Therapy - Oncolytics
